T. MIYAMOTO

Pyridonecarboxylic acids as antibacterial agents. Part 14. Synthesis and structure-activity relationships of 5-substituted 6,8-difluoroquinolones, including sparfloxacin, a new quinolone antibacterial agent with improved potency

T. MIYAMOTO, Junichi Matsumoto, K. CHIBA et al. · Journal of Medicinal Chemistry · 1990 · 129 citations

Bioorganic Chemistry, Antibiotic Adjuvant, Antimicrobial Chemotherapy +20

1,4-Dihydro-4-oxopyridinecarboxylic acids as antibacterial agents. 2. Synthesis and structure-activity relationships of 1,6,7-trisubstituted 1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids, including enoxacin, a new antibacterial agent

Junichi Matsumoto, T. MIYAMOTO, Akira Minamida et al. · Journal of Medicinal Chemistry · 1984 · 90 citations

Organic Chemistry, 1,6,7-Trisubstituted 1,4-Dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acids, Antimicrobial Chemotherapy +19

Pyridonecarboxylic acids as antibacterial agents. Synthesis and antibacterial activity of 7-(3-amino-1-pyrrolidinyl)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid and its analogs

Hiroshi Egawa, T. MIYAMOTO, Akira Minamida et al. · Journal of Medicinal Chemistry · 1984 · 41 citations

Antibacterial Agents, Antibacterial Activity, Organic Chemistry +16

Synthesis of fluorinated pyridines by the balz‐schiemann reaction. An alternative route to enoxacin, a new antibacterial pyridonecarboxylic acid

Junichi Matsumoto, T. MIYAMOTO, Akira Minamida et al. · Journal of Heterocyclic Chemistry · 1984 · 35 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Pyridines 7 +15

A new synthesis of 7H-pyrido(1,2,3-de)(1,4)benzoxazine derivatives including an antibacterial agent, ofloxacin.

Hiroshi Egawa, T. MIYAMOTO, Junichi Matsumoto · Chemical and Pharmaceutical Bulletin · 1986 · 31 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Heterocyclic +14