Ameeta A. Patel

Gain-of-Function Mutant p53 Promotes Cell Growth and Cancer Cell Metabolism via Inhibition of AMPK Activation

Ge Zhou, Jiping Wang, Mei Zhao et al. · Molecular Cell · 2014 · 233 citations

Medicine, Cancer Biology, Cell Biology +13

Evolutionary Action Score of <i>TP53</i> Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer

David M. Neskey, Abdullah A. Osman, Thomas J. Ow et al. · Cancer Research · 2015 · 159 citations · Full text

Medicine, Molecular Biology, Oncology +17

Head and neck cancer organoids established by modification of the CTOS method can be used to predict in vivo drug sensitivity

Noriaki Tanaka, Abdullah A. Osman, Yoko Takahashi et al. · Oral Oncology · 2018 · 144 citations · Full text

Medicine, Oncology, Pharmacology +17

COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms

Antje Lindemann, Ameeta A. Patel, Natalie L. Silver et al. · Clinical Cancer Research · 2019 · 125 citations

Medicine, Oncology, Pharmacology +13

Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-Risk <i>TP53</i> Mutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence

Abdullah A. Osman, Marcus M. Monroe, Marcus V. Ortega Alves et al. · Molecular Cancer Therapeutics · 2014 · 112 citations

Medicine, Oncology, Pharmacology +15