Synthesis, biological evaluation and molecular docking study of benzimidazole derivatives as α-glucosidase inhibitors and anti-diabetes candidates

Shawkat Hayat, Hayat Ullah, Fazal Rahim, +9

Journal of Molecular Structure

Molecular PharmacologyDerivativesBiochemistryBenzimidazole DerivativesMedicine +8

In vitro α-glucosidase and α-amylase inhibitory potential and molecular docking studies of benzohydrazide based imines and thiazolidine-4-one derivatives

Hayat Ullah, Imad Uddin, Fazal Rahim, +10

Journal of Molecular Structure

Molecular PharmacologyBiochemistryMedicineRational Drug Designα-Amylase Inhibitory Potential +7

Synthesis of benzimidazole derivatives as potent inhibitors for α-amylase and their molecular docking study in management of type-II diabetes

Shafqat Hussain, Muhammad Taha, Fazal Rahim, +11

Journal of Molecular Structure

DerivativesBiochemistryBenzimidazole DerivativesMedicineNatural Sciences +9

Exploring efficacy of indole-based dual inhibitors for α-glucosidase and α-amylase enzymes: In silico, biochemical and kinetic studies

Abdel‐Nasser Kawde, Muhammad Taha, Raneem Saud Alansari, +13

International Journal of Biological Macromolecules

α-Amylase EnzymesBiochemistryNatural SciencesBiocatalysisMedicine +7

Isatin based thiosemicarbazide derivatives as potential inhibitor of α-glucosidase, synthesis and their molecular docking study

Fazal Rahim, Muhammad Taha, Naveed Iqbal, +10

Journal of Molecular Structure

Thiosemicarbazide DerivativesMedicinal ChemistryDiversity Oriented SynthesisBiochemistryNatural Sciences +12

Synthesis of Novel Triazinoindole-Based Thiourea Hybrid: A Study on α-Glucosidase Inhibitors and Their Molecular Docking

Muhammad Taha, Foziah Alshamrani, Fazal Rahim, +6

Molecules

New oxadiazole bearing thiosemicarbazide analogues: Synthesis, anti-alzheimer inhibitory potential and their molecular docking study

Hayat Ullah, Fatima Fayyaz, Amjad Hussain, +8

Chemical Data Collections

Combinatorial ChemistryMedicinal ChemistryBiochemistryNatural SciencesAnti-alzheimer Inhibitory Potential +5

Exploring thiazole-based Schiff base analogs as potent α-glucosidase and α-amylase inhibitor: their synthesis and in-silico study

Muhammad Taha, Shawkat Hayat, Fazal Rahim, +7

Journal of Molecular Structure

Medicinal ChemistryBiochemistryIn-silico StudyNatural SciencesMedicine +8

Synthesis, molecular docking study of thiazole derivatives and exploring their dual inhibitor potentials against α-amylase and α-glucosidase

Hayat Ullah, Nisar Ahmad, Fazal Rahim, +9

Chemical Data Collections

Inhibitory ActivityMedicinal ChemistryDerivativesBiochemistryThiazole Derivatives +9

Synthesis, in vitro evaluation and molecular docking studies of hybrid 4-quinolinyl bearing 1,3,4-thiadiazole-2-amine as a new inhibitor of α-amylase and α-glucosidase

Muhammad Taha, Aftab Ahmad Khan, Fazal Rahim, +9

Journal of Molecular Structure

Medicinal ChemistryBiochemistryMedicineNatural SciencesNew Inhibitor +7