Samuel P. Rowbotham

EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors

Christine M. Fillmore, Chunxiao Xu, Pooja Desai et al. · Nature · 2015 · 252 citations · Full text

Ezh2 Inhibition, Tumor Biology, Oncology +11

Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis

Allison N. Lau, Stephen J. Curtis, Christine M. Fillmore et al. · The EMBO Journal · 2014 · 199 citations · Full text

Yap/taz Activity Contribute, Oncology, Medicine +9

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

Samuel P. Rowbotham, Leila Barki, Ana Neves‐Costa et al. · Molecular Cell · 2011 · 184 citations · Full text

Chromatin, Transcriptional Regulation, Silent Chromatin +10

Organoids Model Transcriptional Hallmarks of Oncogenic KRAS Activation in Lung Epithelial Progenitor Cells

Antonella F. M. Dost, Aaron L. Moye, Marall Vedaie et al. · Cell stem cell · 2020 · 162 citations · Full text

Transcriptional Regulation, Developmental Biology, Oncogenic Kras Activation +6

H3K9 methyltransferases and demethylases control lung tumor-propagating cells and lung cancer progression

Samuel P. Rowbotham, Fei Li, Antonella F. M. Dost et al. · Nature Communications · 2018 · 77 citations · Full text