Arnold J. Gutierrez

Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines

Richard W. Wagner, Mark D. Matteucci, Jason G. Lewis et al. · Science · 1993 · 406 citations

Life Sciences, Molecular Biology, Molecular Genetics +17

5-Heteroaryl-2'-deoxyuridine Analogs. Synthesis and Incorporation into High-Affinity Oligonucleotides

Arnold J. Gutierrez, Terry Terhorst, Mark D. Matteucci et al. · Journal of the American Chemical Society · 1994 · 112 citations

Pharmacy, Chemistry, Molecular Biology +12

Antisense Gene Inhibition by C-5-Substituted Deoxyuridine-Containing Oligodeoxynucleotides

Arnold J. Gutierrez, Mark D. Matteucci, Deborah Grant et al. · Biochemistry · 1997 · 60 citations

Life Sciences, Molecular Biology, Gene Expression +13

The intramolecular Diels-Alder cycloaddition of N-dienoyl acrylimidates. An efficient approach for the synthesis of hexahydroisoquinolones and hexahydroisoindolones

Arnold J. Gutierrez, Kenneth J. Shea, John J. Svoboda · The Journal of Organic Chemistry · 1989 · 54 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Preparation of Perhydroisoquinolines via the Intramolecular Diels−Alder Reaction of <i>N</i>-3,5-Hexadienoyl Ethyl Acrylimidates:  A Formal Synthesis of (±)-Reserpine

Steven M. Sparks, Arnold J. Gutierrez, Kenneth J. Shea · The Journal of Organic Chemistry · 2003 · 24 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13