Lee B. Meakin

Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition

Toshihiro Sugiyama, Lee B. Meakin, William J. Browne et al. · Journal of Bone and Mineral Research · 2012 · 208 citations · Full text

Medicine, Orthopedic Surgery, Physiology +15

Estrogen Receptor α Mediates Proliferation of Osteoblastic Cells Stimulated by Estrogen and Mechanical Strain, but Their Acute Down-regulation of the Wnt Antagonist Sost Is Mediated by Estrogen Receptor β

Gabriel L. Galea, Lee B. Meakin, Toshihiro Sugiyama et al. · Journal of Biological Chemistry · 2013 · 124 citations · Full text

Medicine, Endocrinology, Bone Metabolism +16

Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes

Lee B. Meakin, Gabriel L. Galea, Toshihiro Sugiyama et al. · Journal of Bone and Mineral Research · 2014 · 108 citations · Full text

Medicine, Animal Sciences, Aging +16

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

Sara H. Windahl, Leanne Saxon, Anna Börjesson et al. · Journal of Bone and Mineral Research · 2012 · 102 citations · Full text

Medicine, Biochemistry, Endocrinology +17

<i>Sost</i> down‐regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

Gabriel L. Galea, Andrew Sunters, Lee B. Meakin et al. · FEBS Letters · 2011 · 97 citations · Full text

Medicine, Molecular Biology, Bone Metabolism +16