Larry DeDionisio

Effect of phosphorothioate modification of oligodeoxynucleotides on specific protein binding.

David A. Brown, Shin Hyeok Kang, S. M. Gryaznov et al. · Journal of Biological Chemistry · 1994 · 341 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +13

Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides.

Christian Beltinger, H. Uri Saragovi, Richard M. Smith et al. · Journal of Clinical Investigation · 1995 · 314 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Oligonucleotide N3'-->P5' phosphoramidates.

Sergei Gryaznov, D. H. Lloyd, Jia-Kuan Chen et al. · Proceedings of the National Academy of Sciences · 1995 · 153 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +17

Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders

Kathleen A. Christie, David Courtney, Larry DeDionisio et al. · Scientific Reports · 2017 · 84 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Mutation-Independent Allele-Specific Editing by CRISPR-Cas9, a Novel Approach to Treat Autosomal Dominant Disease

Kathleen A. Christie, Louise J. Robertson, Caroline Conway et al. · Molecular Therapy · 2020 · 28 citations · Full text

Life Sciences, Genetics, Molecular Biology +15