Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs

Ahmad Sharanek, Audrey Burban, Matthew Burbank, +4

Scientific Reports

OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation

Ahmad Sharanek, Audrey Burban, Matthew Laaper, +4

Nature Communications

Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes

Pamela Bachour-El Azzi, Ahmad Sharanek, Audrey Burban, +6

Toxicological Sciences

In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes

Georg Tascher, Audrey Burban, Sandrine Camus, +7

Cells

Reference Functional StatusFatty Liver DiseaseCholangiopathiesRobust SurrogateHeparg Cells +21

Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis

Joris Guyon, Ignacio Fernández‐Moncada, Claire Larrieu, +29

EMBO Molecular Medicine

Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes

Audrey Burban, Ahmad Sharanek, Christiane Guguen‐Guillouzo, +1

Free Radical Biology and Medicine

InflammationHepatologyBiochemistryMedicineLiver Physiology +12

Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG Hepatocytes

Ahmad Sharanek, Audrey Burban, Lydie Humbert, +4

Toxicological Sciences

Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis

Matthew Burbank, Audrey Burban, Ahmad Sharanek, +3

Drug Metabolism and Disposition

Histamine Potentiates N-Methyl-d-aspartate Receptors by Interacting with an Allosteric Site Distinct from the Polyamine Binding Site

Audrey Burban, Raphaël Faucard, Vincent Armand, +3

Journal of Pharmacology and Experimental Therapeutics

Transcriptional control of brain tumor stem cells by a carbohydrate binding protein

Ahmad Sharanek, Audrey Burban, Aldo Hernández-Corchado, +5

Cell Reports

Cancer BiologyGliomaTumor BiologyTranscriptional RegulationSignaling Pathway +17