Claudia Jessen‐Trefzer

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

Feng Wang, Dhinakaran Sambandan, Rajkumar Halder et al. · Proceedings of the National Academy of Sciences · 2013 · 225 citations · Full text

Drug Target, Microbial Pathogens, Tuberculosis Prevention +25

Benzothiazinones: Prodrugs That Covalently Modify the Decaprenylphosphoryl-β-<scp>d</scp>-ribose 2′-epimerase DprE1 of <i>Mycobacterium tuberculosis</i>

Claudia Jessen‐Trefzer, Rengifo-Gonzalez Monica, Marlon J. Hinner et al. · Journal of the American Chemical Society · 2010 · 215 citations · Full text

Bioorganic Chemistry, Antimicrobial Chemotherapy, Chemical Biology +18

The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity

Georg E. Winter, Branka Radic-Sarikas, Cristina Mayor‐Ruiz et al. · Nature Chemical Biology · 2014 · 182 citations · Full text

Genome Instability, Natural Sciences, Dna Replication +3

Benzothiazinones Are Suicide Inhibitors of Mycobacterial Decaprenylphosphoryl-β-<scp>d</scp>-ribofuranose 2′-Oxidase DprE1

Claudia Jessen‐Trefzer, Henrieta Škovierová, Silvia Buroni et al. · Journal of the American Chemical Society · 2011 · 175 citations · Full text

Bioorganic Chemistry, Btz-resistant Strains, Antimicrobial Chemotherapy +16

The RNA‐binding protein HuR/ELAVL1 regulates IFN‐β mRNA abundance and the type I IFN response

Barbara Herdy, Thomas Karonitsch, Gregory I. Vladimer et al. · European Journal of Immunology · 2015 · 59 citations · Full text

Engineering, Molecular Regulation, Genetics +26