Patrick H. Roseboom

The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland.

David C. Klein, S L Coon, Patrick H. Roseboom et al. · PubMed · 1997 · 555 citations

Life Sciences, Biochemistry, Physiology +16

Pineal Serotonin <i>N</i> -Acetyltransferase: Expression Cloning and Molecular Analysis

Steven L. Coon, Patrick H. Roseboom, Rubén Baler et al. · Science · 1995 · 342 citations

Life Sciences, Biochemistry, Molecular Biology +17

Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland.

Patrick H. Roseboom, S L Coon, Rubén Baler et al. · Endocrinology · 1996 · 314 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Natural melatonin `knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase

Patrick H. Roseboom, M.A.A. Namboodiri, Drazen B. Zimonjic et al. · Molecular Brain Research · 1998 · 296 citations

Life Sciences, Neuroscience, Pharmacology +17

Melatonin Production: Proteasomal Proteolysis in Serotonin <i>N</i> -Acetyltransferase Regulation

Jonathan A. Gastel, Patrick H. Roseboom, Peter A. Rinaldi et al. · Science · 1998 · 285 citations

Life Sciences, Biochemistry, Pharmacology +17