Manisha U. Lotlikar

3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi et al. · Bioorganic & Medicinal Chemistry · 2019 · 114 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Structure-activity relationships for analogs of the tuberculosis drug bedaquiline with the naphthalene unit replaced by bicyclic heterocycles

Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi et al. · Bioorganic & Medicinal Chemistry · 2018 · 79 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units

Peter J. Choi, Hamish S. Sutherland, Amy S.T. Tong et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 58 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Adrian Blaser, Hamish S. Sutherland, Amy S.T. Tong et al. · Bioorganic & Medicinal Chemistry · 2019 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Hamish S. Sutherland, Amy S.T. Tong, Peter J. Choi et al. · Bioorganic & Medicinal Chemistry · 2019 · 37 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6