Eliane Mandine

Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands

Gaëlle Pennarun, Christine Granotier, Laurent Gauthier et al. · Oncogene · 2005 · 235 citations

Life Sciences, Molecular Biology, Oncology +15

Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase

Thibault Lemarteleur, Dennis Gómez, Rajaa Boujemaa‐Paterski et al. · Biochemical and Biophysical Research Communications · 2004 · 212 citations

Life Sciences, Genetics, Molecular Biology +11

Evidence that monoclonal antibody production kinetics is related to the integral of the viable cells curve in batch systems

James Renard, Roberto Spagnoli, C. Mazier et al. · Biotechnology Letters · 1988 · 190 citations

Pharmacy, Immunology, Monoclonal Antibodies +7

SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design:  Application to the Discovery of Nanomolar Inhibitors of Src SH2

Dominique Lesuisse, Gudrun Lange, Pierre Deprez et al. · Journal of Medicinal Chemistry · 2002 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Requirements for Specific Binding of Low Affinity Inhibitor Fragments to the SH2 Domain of^pp60Src Are Identical to Those for High Affinity Binding of Full Length Inhibitors

Gudrun Lange, Dominique Lesuisse, Pierre Deprez et al. · Journal of Medicinal Chemistry · 2003 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17