Dennis Gómez

Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands

Gaëlle Pennarun, Christine Granotier, Laurent Gauthier et al. · Oncogene · 2005 · 234 citations

Neuro-oncology, Glioma, Human Glioma Cells +11

Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing

Dennis Gómez · Nucleic Acids Research · 2004 · 233 citations · Full text

Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase

Thibault Lemarteleur, Dennis Gómez, Rajaa Boujemaa‐Paterski et al. · Biochemical and Biophysical Research Communications · 2004 · 212 citations

Transcriptional Regulation, Natural Sciences, Molecular Biology +5

Telomestatin-induced Telomere Uncapping Is Modulated by POT1 through G-overhang Extension in HT1080 Human Tumor Cells

Dennis Gómez, Thomas Wenner, Bertrand Brassart et al. · Journal of Biological Chemistry · 2006 · 202 citations · Full text

The G-quadruplex Ligand Telomestatin Inhibits POT1 Binding to Telomeric Sequences <i>In vitro</i> and Induces GFP-POT1 Dissociation from Telomeres in Human Cells

Dennis Gómez, Marie-Françoise O’Donohue, Thomas Wenner et al. · Cancer Research · 2006 · 199 citations