Brent E. Wurfel

Putative Neuroprotective and Neurotoxic Kynurenine Pathway Metabolites Are Associated with Hippocampal and Amygdalar Volumes in Subjects with Major Depressive Disorder

Jonathan Savitz, Wayne C. Drevets, Chelsey M. Smith et al. · Neuropsychopharmacology · 2014 · 266 citations · Full text

Medicine, Neurobiology, Neuroscience +8

Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder

Jonathan Savitz, Wayne C. Drevets, Brent E. Wurfel et al. · Brain Behavior and Immunity · 2015 · 202 citations

Medicine, Pharmacology, Psychiatry +12

Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder

Timothy B. Meier, Wayne C. Drevets, Brent E. Wurfel et al. · Brain Behavior and Immunity · 2015 · 171 citations · Full text

Life Sciences, Neuroscience, Psychiatry +11

Treatment of bipolar depression with minocycline and/or aspirin: an adaptive, 2×2 double-blind, randomized, placebo-controlled, phase IIA clinical trial

Jonathan Savitz, T. Kent Teague, Masaya Misaki et al. · Translational Psychiatry · 2018 · 138 citations · Full text

Medicine, Pharmacology, Psychiatry +10

Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder

Jonathan Savitz, Robert Dantzer, Brent E. Wurfel et al. · Psychoneuroendocrinology · 2014 · 135 citations · Full text

Medicine, Neurobiology, Neuroscience +9