Kozo Ikoma

Interleukin-1beta induces substance P release from primary afferent neurons through the cyclooxygenase-2 system.

Atsuko Inoue, Kozo Ikoma, Norimitsu Morioka et al. · PubMed · 1999 · 167 citations

Life Sciences, Neurobiology, Neuroscience +17

Interleukin‐1β‐induced substance P release from rat cultured primary afferent neurons driven by two phospholipase A2 enzymes: secretory type IIA and cytosolic type IV

Norimitsu Morioka, Kazumi Takeda, Kei Kumagai et al. · Journal of Neurochemistry · 2002 · 55 citations

Life Sciences, Biochemistry, Pharmacology +16

Nitric oxide synergistically potentiates interleukin-1β-induced increase of cyclooxygenase-2 mRNA levels, resulting in the facilitation of substance P release from primary afferent neurons: involvement of cGMP-independent mechanisms

Norimitsu Morioka, Atsuko Inoue, Tomohiko Hanada et al. · Neuropharmacology · 2002 · 48 citations

Life Sciences, Neurobiology, Neuroscience +17