Zijin Xu

Antibody Conjugation of a Chimeric BET Degrader Enables <i>in vivo</i> Activity

Thomas H. Pillow, Pragya Adhikari, Robert A. Blake et al. · ChemMedChem · 2019 · 196 citations

Pharmacy, Medicinal Chemistry, Oncology +17

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 169 citations

Pharmacy, Biochemistry, Medicinal Chemistry +17

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 150 citations

Pharmacy, Oncology, Pharmacology +17

Discovery of Peptidomimetic Antibody–Drug Conjugate Linkers with Enhanced Protease Specificity

BinQing Wei, Janet Gunzner-Toste, Hui Yao et al. · Journal of Medicinal Chemistry · 2017 · 106 citations

Pharmacy, Medicinal Chemistry, Oncology +17

Development of Efficient Chemistry to Generate Site-Specific Disulfide-Linked Protein– and Peptide–Payload Conjugates: Application to THIOMAB Antibody–Drug Conjugates

Jack Sadowsky, Thomas H. Pillow, Jinhua Chen et al. · Bioconjugate Chemistry · 2017 · 61 citations

Pharmacy, Biotechnology, Pharmaceutics +17