SEA0400, a Novel and Selective Inhibitor of the Na+-Ca2+ Exchanger, Attenuates Reperfusion Injury in the in Vitro and in Vivo Cerebral Ischemic Models

Naohisa Arakawa, Kazuhiro Takuma, Yoko Kishida, +7

Journal of Pharmacology and Experimental Therapeutics

HET0016, a potent and selective inhibitor of 20‐HETE synthesizing enzyme

Noriyuki Miyata, Kazuo Taniguchi, Takayuki Seki, +9

British Journal of Pharmacology

Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia–reperfusion injuries

Kenzo Takahashi, Teisuke Takahashi, Taizo Suzuki, +7

European Journal of Pharmacology

Myocardial Ischemia–reperfusion InjuriesCardiovascular DiseaseMedicinePhysiologyCardiovascular Pharmacology +8

Effect of taurine on cholesterol metabolism in hamsters: Up-regulation of low density lipoprotein (LDL) receptor by taurine

Shigeru Murakami, Yukiko Kondo, Yoshihisa Toda, +4

Life Sciences

Cholesterol MetabolismOxysterolMedicinePhysiologyHyperlipidemia +5

Pyrazole and Isoxazole Derivatives as New, Potent, and Selective 20-Hydroxy-5,8,11,14-eicosatetraenoic Acid Synthase Inhibitors

Toshio Nakamura, Masakazu Sato, Hiroyuki Kakinuma, +5

Journal of Medicinal Chemistry

Pharmaceutical ScienceBioorganic ChemistryIsoxazole DerivativesPharmacotherapyChemical Biology +14

Synthesis and Antibacterial Activity of a Novel Series of Acylides:  3-<i>O</i>-(3-Pyridyl)acetylerythromycin A Derivatives

Tetsuya Tanikawa, Toshifumi Asaka, Masato Kashimura, +6

Journal of Medicinal Chemistry

Antibacterial ActivityKlebsiella PneumoniaeOrganic ChemistryChemical DerivativeDrug Resistance +18

Synthesis and Antibacterial Activity of Acylides (3-<i>O</i>-Acyl-erythromycin Derivatives):  A Novel Class of Macrolide Antibiotics

Tetsuya Tanikawa, Toshifumi Asaka, Masato Kashimura, +6

Journal of Medicinal Chemistry

Antibacterial ActivityNext-generation Macrolide AntibioticsAntimicrobial ChemotherapyMacrolide AntibioticsAntibiotic Resistance +15

Effects of taurine on serum cholesterol levels and development of atherosclerosis in spontaneously hyperlipidaemic mice

Yoshibumi Matsushima, Takumi Sekine, Yukiko Kondo, +4

Clinical and Experimental Pharmacology and Physiology

Serum Cholesterol LevelsHyperlipidemiaOxidative StressInflammationMetabolic Syndrome +15

Taurine Inhibits Development Of Atherosclerotic Lesions In apolipoprotein E‐Deficient Mice<b>^‡</b>

Yukiko Kondo, Yoshihisa Toda, Hideaki Kitajima, +4

Clinical and Experimental Pharmacology and Physiology

Discovery of a N′-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor

Masakazu Sato, Takaaki Ishii, Yuko Kobayashi-Matsunaga, +4

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryNatural SciencesMedicineDrug Development +6