Sam Giannakoulias

Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput <i>in silico</i> screening

John J. Ferrie, Zsofia Lengyel‐Zhand, Bieneke Janssen et al. · Chemical Science · 2020 · 57 citations · Full text

Pharmacy, Chemical Biology, Molecular Biology +16

A “Clickable” Photoconvertible Small Fluorescent Molecule as a Minimalist Probe for Tracking Individual Biomolecule Complexes

Joomyung V. Jun, Conor M. Haney, Richard J. Karpowicz et al. · Journal of the American Chemical Society · 2019 · 51 citations

Natural Sciences, Biophysics, Molecular Biology +16

Studies of Thioamide Effects on Serine Protease Activity Enable Two-Site Stabilization of Cancer Imaging Peptides

Taylor M. Barrett, Xing S. Chen, Chunxiao Liu et al. · ACS Chemical Biology · 2020 · 27 citations · Full text

Life Sciences, Biochemistry, Oncology +16

Rosetta custom score functions accurately predict ΔΔ <i>G</i> of mutations at protein–protein interfaces using machine learning

Sumant R. Shringari, Sam Giannakoulias, John J. Ferrie et al. · Chemical Communications · 2020 · 20 citations

Life Sciences, Bioinformatics, Molecular Biology +11

Rational design of thioamide peptides as selective inhibitors of cysteine protease cathepsin L

Hoang Anh T. Phan, Sam Giannakoulias, Taylor M. Barrett et al. · Chemical Science · 2021 · 20 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17