Sakshi Gulati

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Nicholas McGranahan, Rachel Rosenthal, Crispin T. Hiley et al. · Cell · 2017 · 1.3K citations · Full text

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

Marco Gerlinger, Stuart Horswell, James Larkin et al. · Nature Genetics · 2014 · 1.2K citations · Full text

Urology, Genitourinary Cancer, Tumor Heterogeneity +7

Olaparib and durvalumab in patients with germline BRCA-mutated metastatic breast cancer (MEDIOLA): an open-label, multicentre, phase 1/2, basket study

Susan M. Domchek, Sophie Postel‐Vinay, Seock‐Ah Im et al. · The Lancet Oncology · 2020 · 435 citations

Phase 1/2, Breast Oncology, Oncology +8

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

Frederick Arce Vargas, Andrew J.S. Furness, Isabelle Solomon et al. · Immunity · 2017 · 425 citations · Full text

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study

Dominic G. Rothwell, Mahmood Ayub, Natalie Cook et al. · Nature Medicine · 2019 · 302 citations

Genetic Testing, Oncology, Cancer Detection +11