Ibrahim Alkanfari

Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant

Ibrahim Alkanfari, Kshitij Gupta, Tahsin Jahan et al. · The Journal of Immunology · 2018 · 80 citations · Full text

Identification of Gain and Loss of Function Missense Variants in MRGPRX2’s Transmembrane and Intracellular Domains for Mast Cell Activation by Substance P

Chalatip Chompunud Na Ayudhya, Saptarshi Roy, Ibrahim Alkanfari et al. · International Journal of Molecular Sciences · 2019 · 69 citations · Full text

Small-Molecule Host-Defense Peptide Mimetic Antibacterial and Antifungal Agents Activate Human and Mouse Mast Cells via Mas-Related GPCRs

Ibrahim Alkanfari, Katie B. Freeman, Saptarshi Roy et al. · Cells · 2019 · 30 citations · Full text

Mast Cell Disorder, Immunology, Cell Death +17

Role of MrgprB2 in Rosacea-Like Inflammation in Mice: Modulation by β-Arrestin 2

Saptarshi Roy, Ibrahim Alkanfari, Shaswati Chaki et al. · Journal of Investigative Dermatology · 2022 · 26 citations · Full text

Inflammation, β-Arrestin 2, Molecular Physiology +10

Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells

Shaswati Chaki, Ibrahim Alkanfari, Saptarshi Roy et al. · Frontiers in Immunology · 2022 · 25 citations · Full text

Mast Cell Disorder, Immunology, Immune Regulation +26