Leo Francis Manley

A flowsheet model for the development of a continuous process for pharmaceutical tablets: An industrial perspective

Salvador García‐Muñoz, Adam S. Butterbaugh, Ian M. Leavesley et al. · AIChE Journal · 2017 · 87 citations

Engineering, Industrial Engineering, Mechanical Engineering +20

Tablet Compression Force as a Process Analytical Technology (PAT): 100% Inspection and Control of Tablet Weight Uniformity

Leo Francis Manley, Jon Hilden, Pablo Antonio Moreno Valero et al. · Journal of Pharmaceutical Sciences · 2018 · 41 citations

Tablet Compression Force, Engineering, Process Analytical Technology +5

On-line monitoring of blend uniformity in continuous drug product manufacturing process—The impact of powder flow rate and the choice of spectrometer: Dispersive vs. FT

Zhenqi Shi, Kathryn C. McGhehey, Ian M. Leavesley et al. · Journal of Pharmaceutical and Biomedical Analysis · 2015 · 33 citations

Blend Uniformity, Drug Manufacture, Process Analytical Technology +8

Characterizing drug product continuous manufacturing residence time distributions of major/minor excipient step changes using near infrared spectroscopy and process parameters

Leo Francis Manley, Zhenqi Shi · International Journal of Pharmaceutics · 2018 · 14 citations

Engineering, Process Parameters, Process Analytical Technology +10