A Pyrrolo-Pyrimidine Derivative Targets Human Primary AML Stem Cells in Vivo

Yoriko Saito, Hitomi Yuki, M. Kuratani, +26

Science Translational Medicine

Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes

Kazue Terasawa, Yuri Tomabechi, Mariko Ikeda, +8

Biochemical and Biophysical Research Communications

BiochemistryProtein AssemblyNatural SciencesLysosome-associated Membrane Proteins-1Distinct Modes +8

Crystal structure of nanoKAZ: The mutated 19 kDa component of Oplophorus luciferase catalyzing the bioluminescent reaction with coelenterazine

Yuri Tomabechi, Takamitsu Hosoya, Haruhiko Ehara, +3

Biochemical and Biophysical Research Communications

Crystal StructureBioorganic ChemistryEngineeringBiochemistryNatural Sciences +6

Structural basis for CRMP2-induced axonal microtubule formation

Shinsuke Niwa, Fumio Nakamura, Yuri Tomabechi, +9

Scientific Reports

Protein stabilization utilizing a redefined codon

Kazumasa Ohtake, Atsushi Yamaguchi, Takahito Mukai, +14

Scientific Reports

Crystal Structure of the Ca2+/Calmodulin-dependent Protein Kinase Kinase in Complex with the Inhibitor STO-609

Mutsuko Kukimoto‐Niino, S. Yoshikawa, Tetsuo Takagi, +11

Journal of Biological Chemistry

Crystal StructureProtein FunctionSignal TransductionBiochemistryNatural Sciences +7

A reproducible and scalable procedure for preparing bacterial extracts for cell-free protein synthesis

Kazushige Katsura, Takayoshi Matsuda, Yuri Tomabechi, +6

The Journal of Biochemistry

EngineeringBioprocess EngineeringProtein SynthesisProtein PurificationAnaerobic Culturing +17

CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation

Tsuyoshi Imasaki, Satoshi Kikkawa, Shinsuke Niwa, +17

eLife

Nucleation IntermediatesProtein FunctionMicrotubule NucleationProtein AssemblyNatural Sciences +10

Crystal Structures of the Armadillo Repeat Domain of Adenomatous Polyposis Coli and Its Complex with the Tyrosine-Rich Domain of Sam68

Ella Czarina Morishita, Kazutaka Murayama, M. Kato-Murayama, +8

Structure

Tyrosine-rich DomainProtein AssemblyBiochemistryNatural SciencesProtein X-ray Crystallography +4

A Novel Pim-1 Kinase Inhibitor Targeting Residues That Bind the Substrate Peptide

Keiko Tsuganezawa, Hisami Watanabe, L.J. Parker, +14

Journal of Molecular Biology

Protein FunctionSignal TransductionPeptide LibraryReceptor Tyrosine KinasePeptide Therapeutic +6