Irène R. Chassagnon

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

Irène R. Chassagnon, Claudia A. McCarthy, Yanni K.‐Y. Chin et al. · Proceedings of the National Academy of Sciences · 2017 · 231 citations · Full text

Life Sciences, Neurology, Neuroscience +17

A Dynamic Pharmacophore Drives the Interaction between Psalmotoxin-1 and the Putative Drug Target Acid-Sensing Ion Channel 1a

Natalie J. Saez, Mehdi Mobli, Michael Bieri et al. · Molecular Pharmacology · 2011 · 93 citations

Medicine, Molecular Biology, Pharmacology +13

PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a

Claudia A. McCarthy, Lachlan D. Rash, Irène R. Chassagnon et al. · Neuropharmacology · 2015 · 76 citations

Medicine, Neuroscience, Pharmacology +17

Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin

Sarah Piper, Lou Brillault, Rosalba Rothnagel et al. · Nature Communications · 2019 · 50 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a

Natalie J. Saez, Evelyne Deplazes, Ben Cristofori‐Armstrong et al. · British Journal of Pharmacology · 2015 · 43 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17