José La Rose

A point mutation in CD28 distinguishes proliferative signals from survival signals

Klaus Okkenhaug, Linda Wu, Kristine M. Garza et al. · Nature Immunology · 2001 · 202 citations

Survival Signals, Signal Transduction, Signaling Pathway +9

Socs1 binds to multiple signalling proteins and suppresses Steel factor-dependent proliferation

Paulo De Sepulveda, Klaus Okkenhaug, José La Rose et al. · The EMBO Journal · 1999 · 202 citations · Full text

Transcriptional Regulation, Sclerostin, Signal Transduction +9

Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism

Noam Levaot, Oleksandr Voytyuk, Ioannis D. Dimitriou et al. · Cell · 2011 · 188 citations · Full text

Biology, Biochemistry, Natural Sciences +3

Autoinhibition of the Kit Receptor Tyrosine Kinase by the Cytosolic Juxtamembrane Region

Perry M. Chan, Subburaj Ilangumaran, José La Rose et al. · Molecular and Cellular Biology · 2003 · 158 citations · Full text

Molecular Biology, Cellular Physiology, Tumor Biology +16

The tumor suppressor activity of SOCS-1

Robert Rottapel, Subburaj Ilangumaran, Chris Neale et al. · Oncogene · 2002 · 130 citations

Signaling Pathway, Medicine, Tumor Suppressor Activity +5