Jia-Rong Liu

High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma

Jia-Rong Liu, Chao‐Wu Yu, Pei-Yun Hung et al. · Biochemical Pharmacology · 2019 · 82 citations

Life Sciences, Cancer Biology, Oncology +17

Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia

Ajit Dhananjay Jagtap, Pei‐Teh Chang, Jia-Rong Liu et al. · European Journal of Medicinal Chemistry · 2014 · 32 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

Acrylamide Functional Group Incorporation Improves Drug-like Properties: An Example with EGFR Inhibitors

Kuen-Da Wu, Grace Shiahuy Chen, Jia-Rong Liu et al. · ACS Medicinal Chemistry Letters · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A highly HDAC6-selective inhibitor acts as a fluorescent probe

Yi-Hsun Ho, Kuang-Jui Wang, Pei-Yun Hung et al. · Organic & Biomolecular Chemistry · 2018 · 26 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of novel anaplastic lymphoma kinase (ALK) and histone deacetylase (HDAC) dual inhibitors exhibiting antiproliferative activity against non-small cell lung cancer

Kangli Wang, T.Y. Yeh, Pei‐Chen Hsu et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2024 · 21 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13