Jia-Rong Liu

High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma

Jia-Rong Liu, Chao‐Wu Yu, Pei-Yun Hung et al. · Biochemical Pharmacology · 2019 · 78 citations

High-selective Hdac6 Inhibitor, Cell Autophagy, Autophagy Modulation +10

Novel acylureidoindolin-2-one derivatives as dual Aurora B/FLT3 inhibitors for the treatment of acute myeloid leukemia

Ajit Dhananjay Jagtap, Pei‐Teh Chang, Jia-Rong Liu et al. · European Journal of Medicinal Chemistry · 2014 · 32 citations · Full text

Hematological Malignancy, Medicinal Chemistry, Novel Acylureidoindolin-2-one Derivatives +10

Acrylamide Functional Group Incorporation Improves Drug-like Properties: An Example with EGFR Inhibitors

Kuen-Da Wu, Grace Shiahuy Chen, Jia-Rong Liu et al. · ACS Medicinal Chemistry Letters · 2018 · 30 citations · Full text

A highly HDAC6-selective inhibitor acts as a fluorescent probe

Yi-Hsun Ho, Kuang-Jui Wang, Pei-Yun Hung et al. · Organic & Biomolecular Chemistry · 2018 · 25 citations

Bioisosteric replacement of an acylureido moiety attached to an indolin-2-one scaffold with a malonamido or a 2/4-pyridinoylamido moiety produces a selectively potent Aurora-B inhibitor

Hsiao-Chun Wang, Ajit Dhananjay Jagtap, Pei‐Teh Chang et al. · European Journal of Medicinal Chemistry · 2014 · 20 citations · Full text

Bioisosteric Replacement, Combinatorial Chemistry, Medicinal Chemistry +11