Mariangela Di Tacchio

Angiopoietin-2-induced blood–brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling

Stefanie Gurnik, Kavi Devraj, Jadranka Macas et al. · Acta Neuropathologica · 2016 · 171 citations · Full text

Life Sciences, Neuroscience, Pharmacology +14

Endothelial cell‐derived angiopoietin‐2 is a therapeutic target in treatment‐naive and bevacizumab‐resistant glioblastoma

Alexander Scholz, Patrick N. Harter, Sebastian Cremer et al. · EMBO Molecular Medicine · 2015 · 170 citations · Full text

Medicine, Neurology, Oncology +17

Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF

Mariangela Di Tacchio, Jadranka Macas, Jakob Weissenberger et al. · Cancer Immunology Research · 2019 · 99 citations · Full text

Medicine, Immunology, Oncology +17

Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood–brain barrier in acute ischemic stroke

Daniel Spitzer, Sylvaine Guérit, Tim Puetz et al. · Acta Neuropathologica · 2022 · 89 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Antibody discovery and engineering by enhanced CRISPR-Cas9 integration of variable gene cassette libraries in mammalian cells

Cristina Parola, Daniel Neumeier, Simon Friedensohn et al. · mAbs · 2019 · 35 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17