Tommy Szeto

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Chunlong Ma, M. Sacco, Brett L. Hurst et al. · Cell Research · 2020 · 885 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +17

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

Chunlong Ma, M. Sacco, Zilei Xia et al. · ACS Central Science · 2021 · 198 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +14

Expedited Approach toward the Rational Design of Noncovalent SARS-CoV-2 Main Protease Inhibitors

Naoya Kitamura, M. Sacco, Chunlong Ma et al. · Journal of Medicinal Chemistry · 2021 · 165 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Boceprevir, Calpain Inhibitors II and XII, and GC-376 Have Broad-Spectrum Antiviral Activity against Coronaviruses

Yanmei Hu, Chunlong Ma, Tommy Szeto et al. · ACS Infectious Diseases · 2021 · 116 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +17

Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir

Zilei Xia, M. Sacco, Yanmei Hu et al. · ACS Pharmacology & Translational Science · 2021 · 98 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17