Xiangyun Amy Chen

PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures

Marc Leshner, Shu Wang, Carrie Lewis et al. · Frontiers in Immunology · 2012 · 451 citations · Full text

Hypercitrullination Induces, Chromatin Decondensation, Apoptosis +25

Small Molecules Efficiently Reprogram Human Astroglial Cells into Functional Neurons

Lei Zhang, Jiu-Chao Yin, Hana Yeh et al. · Cell stem cell · 2015 · 277 citations · Full text

Neuroregeneration, Molecular Neuroscience, Cellular Neuroscience +9

Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity

Yuji Wang, Pingxin Li, Shu Wang et al. · Journal of Biological Chemistry · 2012 · 157 citations · Full text

Cofilin Aggregation Blocks Intracellular Trafficking and Induces Synaptic Loss in Hippocampal Neurons

Joseph Cichon, Chicheng Sun, Ben Chen et al. · Journal of Biological Chemistry · 2011 · 96 citations · Full text

ATF4 Gene Network Mediates Cellular Response to the Anticancer PAD Inhibitor YW3-56 in Triple-Negative Breast Cancer Cells

Shu Wang, Xiangyun Amy Chen, Jing Hu et al. · Molecular Cancer Therapeutics · 2015 · 72 citations · Full text

Cancer Research, Breast Oncology, Medicine +14