Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT

Richard W. Meek, James N. Blaza, Jil A. Busmann, +3

Nature Communications

Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications

Manuel González‐Cuesta, Peter Sidhu, Roger A. Ashmus, +10

Journal of the American Chemical Society

A Direct Fluorescent Activity Assay for Glycosyltransferases Enables Convenient High‐Throughput Screening: Application to <i>O</i>‐GlcNAc Transferase

Matthew G. Alteen, Christina Gros, Richard W. Meek, +11

Angewandte Chemie International Edition

Potent De Novo Macrocyclic Peptides That Inhibit O‐GlcNAc Transferase through an Allosteric Mechanism

Matthew G. Alteen, Hayden Peacock, Richard W. Meek, +5

Angewandte Chemie International Edition

Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase

Matthew G. Alteen, Richard W. Meek, Subramania Kolappan, +7

Proceedings of the National Academy of Sciences