SynergyFinder Plus: Toward Better Interpretation and Annotation of Drug Combination Screening Datasets

Shuyu Zheng, Wenyu Wang, Jehad Aldahdooh, +5

Genomics Proteomics & Bioinformatics

mTORC1 Regulates Mitochondrial Integrated Stress Response and Mitochondrial Myopathy Progression

Nahid Khan, Joni Nikkanen, Shuichi Yatsuga, +7

Cell Metabolism

Mitochondrial MyopathyMitophagyMitochondrial FunctionMitochondrial DynamicPhysiology +5

Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

Eija Pirinen, Mari Auranen, Nahid Khan, +15

Cell Metabolism

Mitochondrial MyopathyMuscle PhysiologyAdult-onset Mitochondrial MyopathyBiochemistryMitochondrial Function +10

DrugComb: an integrative cancer drug combination data portal

Bulat Zagidullin, Jehad Aldahdooh, Shuyu Zheng, +8

Nucleic Acids Research

Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans

Timothy A. Scott, Leonor M. Quintaneiro, Povilas Norvaišas, +13

Cell

Drug combination sensitivity scoring facilitates the discovery of synergistic and efficacious drug combinations in cancer

Alina Malyutina, Muntasir Mamun Majumder, Wenyu Wang, +3

PLoS Computational Biology

Drug TargetEngineeringHit IdentificationEfficacious Drug CombinationsSynergy Levels +17

Faecal and serum metabolomics in paediatric inflammatory bowel disease

Kaija‐Leena Kolho, Alberto Pessia, Tytti Jaakkola, +2

Journal of Crohn s and Colitis

Surveillance of European Domestic Pig Populations Identifies an Emerging Reservoir of Potentially Zoonotic Swine Influenza A Viruses

Dinah Henritzi, Philipp P. Petric, Nicola S. Lewis, +19

Cell Host & Microbe

Virus EpidemiologyEmerging Infectious DiseasesEmergent VirusVirologyPorcine Disease +5

CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs

Désirée Schatton, David Pla‐Martín, Marie‐Charlotte Marx, +10

The Journal of Cell Biology

A community challenge for a pancancer drug mechanism of action inference from perturbational profile data

Eugene F. Douglass, Robert J. Allaway, Bence Szalai, +25

Cell Reports Medicine