The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

Chikahide Masutani, Rika Kusumoto, Ayumi Yamada, +7

Nature

Natural SciencesGeneticsDna ReplicationMolecular BiologyMolecular Genetics +5

Preventive and therapeutic effects in rats of hepatocyte growth factor infusion on liver fibrosis/cirrhosis

Yukihiko Matsuda, Kunio Matsumoto, Ayumi Yamada, +5

Hepatology

Liver FibrosisImmunologyPathologyTherapeutic EffectsCholangiopathies +19

UV-B Radiation Induces Epithelial Tumors in Mice Lacking DNA Polymerase η and Mesenchymal Tumors in Mice Deficient for DNA Polymerase ι

Tsuyoshi Ohkumo, Yuji Kondo, Masayuki Yokoi, +9

Molecular and Cellular Biology

EngineeringRadiation EffectPathologyDermatologyRadiation Biology +22

Identification and Characterization of XPC-Binding Domain of hHR23B

Chikahide Masutani, Marito Araki, Kaoru Sugasawa, +7

Molecular and Cellular Biology

Xpc Ner ActivityProtein FunctionBiochemistryNatural SciencesHhr23b Protein +7

Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase  

Ayumi Yamada, Chikahide Masutani, Shigenori Iwai, +1

Nucleic Acids Research

A Role for Cdc2- and PP2A-Mediated Regulation of Emi2 in the Maintenance of CSF Arrest

Qiju Wu, Yanxiang Guo, Ayumi Yamada, +11

Current Biology

Signal TransductionPp2a-mediated RegulationCsf ArrestCell DeathRadiation Oncology +5

Aven-Dependent Activation of ATM Following DNA Damage

Jessie Yanxiang Guo, Ayumi Yamada, Taisuke Kajino, +13

Current Biology

Genome InstabilityDna DamageNatural SciencesGeneticsGenomic Mechanism +6

Effect of a Novel Antibiotic, Heliquinomycin, on DNA Helicase and Cell Growth.

Makoto Chino, Kiyohiro Nishikawa, Ayumi Yamada, +5

The Journal of Antibiotics

Design and synthesis of nonsteroidal progesterone receptor antagonists based on C,C′-diphenylcarborane scaffold as a hydrophobic pharmacophore

Shinya Fujii, Ayumi Yamada, Eiichi Nakano, +4

European Journal of Medicinal Chemistry

Molecular PharmacologyPharmaceutical ScienceMedicinePharmacological AgentHydrophobic Pharmacophore +6

Reconstitution of damage DNA excision reaction from SV40 minichromosomes with purified nucleotide excision repair proteins

Marito Araki, Chikahide Masutani, Takafumi Maekawa, +7

Mutation Research/DNA Repair

ChromatinGenome InstabilityChromatin StructureChromatin RemodelingNatural Sciences +7