A guide to analysis of mouse energy metabolism

Matthias H. Tschöp, John R. Speakman, Jonathan R. S. Arch, +22

Nature Methods

Energy HomeostasisEnergy MetabolismBiochemistryPhysiologyMouse Energy Metabolism +5

Agouti-related peptide–expressing neurons are mandatory for feeding

Eva Gropp, Marya Shanabrough, Erzsébet Borók, +10

Nature Neuroscience

Molecular NeuroscienceSynaptic TransmissionPhysiologyAgouti-related Peptide–expressing NeuronsPeptide Science +7

Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production

A. Christine Könner, Ruth Janoschek, Leona Plum, +11

Cell Metabolism

Molecular PhysiologySignal TransductionMolecular NeuroscienceHepatic Glucose ProductionInsulin Action +10

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

Leona Plum

Journal of Clinical Investigation

FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake

Hongxia Ren, Ian J. Orozco, Ya Su, +7

Cell

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

Leona Plum, Hua Lin, Roxanne Dutia, +10

Nature Medicine

ObesityMetabolic SyndromeHypothalamic CircuitsEnergy HomeostasisMedicine +10

Peripheral Hyperinsulinemia Promotes Tau Phosphorylation In Vivo

S Freude, Leona Plum, J Schnitker, +5

Diabetes

Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons

Hua Lin, Leona Plum, Hiraku Ono, +6

Diabetes

Insulin ReceptorInsulin SignalingGastrointestinal Peptide HormoneObesityMetabolic Syndrome +20

Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation

Leona Plum, Eva Rother, Heike Münzberg, +12

Cell Metabolism

ObesityMetabolic SyndromeEnergy HomeostasisDevelopmental BiologySignal Transduction +13

Myeloid Cell-Restricted Insulin Receptor Deficiency Protects Against Obesity-Induced Inflammation and Systemic Insulin Resistance

Jan Mauer, Bhagirath Chaurasia, Leona Plum, +6

PLoS Genetics