Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

Pernille Jansen, Anja W. Fjorback, Simon Glerup, +9

Nature Neuroscience

The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion

Camilla Gustafsen, Mads Kjølby, Mette Nyegaard, +7

Cell Metabolism

APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1

Masaya Tachibana, Marie‐Louise Holm, Chia‐Chen Liu, +12

Journal of Clinical Investigation

Apoe GeneNeurochemical BiomarkersSynaptic SignalingSocial SciencesNeurobiology Of Disease +15

Heparan sulfate proteoglycans present PCSK9 to the LDL receptor

Camilla Gustafsen, Ditte Olsen, Joachim Vilstrup, +11

Nature Communications

Sortilin and SorLA Display Distinct Roles in Processing and Trafficking of Amyloid Precursor Protein

Camilla Gustafsen, Simon Glerup, Lone Tjener Pallesen, +5

Journal of Neuroscience

Protein SecretionSynaptic TransmissionMolecular BiologyAmyloid Precursor ProteinSynaptic Signaling +22

SorCS2 is required for BDNF-dependent plasticity in the hippocampus

Simon Glerup, Simon Mølgaard, Andrew H. Smith, +10

Molecular Psychiatry

Synaptic PlasticityMolecular NeuroscienceBdnf-dependent PlasticityCortical RemodelingNeuroscience +3

Sortilin-Related Receptor SORCS3 Is a Postsynaptic Modulator of Synaptic Depression and Fear Extinction

Tilman Breiderhoff, Gitte Bundgaard Christiansen, Lone Tjener Pallesen, +3

PLoS ONE

NeurotransmitterAffective NeuroscienceNeurotransmissionOrphan ReceptorGlutamate Receptors +19

SorCS2 Regulates Dopaminergic Wiring and Is Processed into an Apoptotic Two-Chain Receptor in Peripheral Glia

Simon Glerup, Ditte Olsen, Camilla Gustafsen, +18

Neuron

Apoptotic Two-chain ReceptorSignal TransductionPeripheral GliaFunctional SelectivityReceptor (Biochemistry) +6

Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

Pernille Bøttger, Simon Glerup, Bodil Gesslein, +12

Scientific Reports

SorLA regulates the activity of lipoprotein lipase by intracellular trafficking

Stine Christensen Klinger, Simon Glerup, Merete K. Raarup, +10

Journal of Cell Science

Proteinlipid InteractionSignal TransductionBiochemistryMedicineTrans Golgi Network +13