Guifeng Lin

SARS-CoV-2 M ^pro inhibitors with antiviral activity in a transgenic mouse model

Jingxin Qiao, Yueshan Li, Rui Zeng et al. · Science · 2021 · 450 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicron

Baoxue Quan, Huiping Shuai, Anjie Xia et al. · Nature Microbiology · 2022 · 101 citations · Full text

Medicine, Infectious Diseases, Pharmacology +8

Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1

Xin Yang, Xuehui Wang, Zheng Xu et al. · Nature Chemical Biology · 2022 · 97 citations

Medicine, Molecular Biology, Pharmacology +16

Structure‐Guided Discovery of a Potent and Selective Cell‐Active Inhibitor of SETDB1 Tudor Domain

Yinping Guo, Xin Mao, Liang Xiong et al. · Angewandte Chemie International Edition · 2021 · 57 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +14

HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing

Nan Liu, Lifang Zhou, Guifeng Lin et al. · Molecular Therapy — Nucleic Acids · 2022 · 57 citations · Full text

Life Sciences, Genetics, Molecular Biology +15