John Affinito

A phase 2, randomized, placebo-controlled study of the efficacy and safety of TAK-063 in subjects with an acute exacerbation of schizophrenia

Thomas A. Macek, Maggie McCue, Xinxin Dong et al. · Schizophrenia Research · 2018 · 57 citations

Medicine, Pharmacology, Psychiatry +10

Clinical implications of directly switching antidepressants in well-treated depressed patients with treatment-emergent sexual dysfunction: a comparison between vortioxetine and escitalopram

Paula L. Jacobsen, George G. Nomikos, Wei Zhong et al. · CNS Spectrums · 2019 · 40 citations · Full text

Pharmacy, Pharmacotherapy, Psychiatry +17

Safety, tolerability, pharmacokinetics, pharmacodynamics, bioavailability and food effect of single doses of soticlestat in healthy subjects

Shining Wang, Grace Chen, Emilio Merlo Pich et al. · British Journal of Clinical Pharmacology · 2021 · 26 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Lack of Effect of Vortioxetine on the Pharmacokinetics and Pharmacodynamics of Ethanol, Diazepam, and Lithium

Grace Chen, George G. Nomikos, John Affinito et al. · Clinical Pharmacokinetics · 2016 · 21 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +9

Pharmacokinetics, pharmacodynamics and safety assessment of multiple doses of soticlestat in healthy volunteers

Shining Wang, Grace Chen, Emilio Merlo Pich et al. · British Journal of Clinical Pharmacology · 2022 · 20 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13