Linghui Hou

Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity

Ziying Hu, Chengdong Zhang, Shuai Wang et al. · Nucleic Acids Research · 2021 · 60 citations · Full text

Engineering, Biomolecular Tool, Molecular Biology +19

Closely related type II-C Cas9 orthologs recognize diverse PAMs

Jingjing Wei, Linghui Hou, Jingtong Liu et al. · eLife · 2022 · 37 citations · Full text

Prediction of base editor off-targets by deep learning

Chengdong Zhang, Yuan Yang, Tao Qi et al. · Nature Communications · 2023 · 29 citations · Full text

Compact SchCas9 Recognizes the Simple NNGR PAM

Shuai Wang, Huilin Mao, Linghui Hou et al. · Advanced Science · 2021 · 26 citations · Full text

Directly targeting BAX for drug discovery: Therapeutic opportunities and challenges

Zhenwei Zhang, Linghui Hou, Dan Liu et al. · Acta Pharmaceutica Sinica B · 2024 · 23 citations · Full text

Heart Failure, Drug Target, Apoptosis +17