Christopher Kimberley

Phenotypic plasticity and genetic control in colorectal cancer evolution

Jacob Househam, Timon Heide, George D. Cresswell et al. · Nature · 2022 · 182 citations · Full text

Medicine, Evolutionary Biology, Genetics +17

Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum‐induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer

Linda Nicholson, Paul Smith, Louise Hiller et al. · International Journal of Cancer · 2009 · 131 citations

Medicine, Molecular Biology, Oncology +17

The co-evolution of the genome and epigenome in colorectal cancer

Timon Heide, Jacob Househam, George D. Cresswell et al. · Nature · 2022 · 125 citations · Full text

Medicine, Genetics, Oncology +17

The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of oestrogen receptor and IGF signalling

L-A Martin, Sunil Pancholi, Christina M.W. Chan et al. · Endocrine Related Cancer · 2005 · 82 citations · Full text

Medicine, Endocrinology, Oncology +12

Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

Yannik Bollen, Ellen Stelloo, Petra van Leenen et al. · Nature Genetics · 2021 · 72 citations · Full text

Life Sciences, Genetics, Oncology +16