Integrative Genomic Profiling of Human Prostate Cancer

Barry S. Taylor, Nikolaus Schultz, Haley Hieronymus, +23

Cancer Cell

UrologyFunctional GenomicsIntegrative Genomic ProfilingGenitourinary CancerCancer Genomics +3

Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer

Chris Tran, Samedy Ouk, Nicola J. Clegg, +16

Science

Androgen ReceptorMedicinal ChemistryUrologySecond-generation AntiandrogenGenitourinary Cancer +10

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

Dong Gao, Ian Vela, Andrea Sboner, +36

Cell

Organoid Cultures DerivedUrologyMedicineOrganoid ModelsProstatic Disease +1

Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade

Vivek Arora, Emily Schenkein, Rajmohan Murali, +9

Cell

Endocrine MechanismMedicineHormonal ReceptorGynecologyGlucocorticoid +4

ARN-509: A Novel Antiandrogen for Prostate Cancer Treatment

Nicola J. Clegg, John Wongvipat, James D. Joseph, +32

Cancer Research

Androgen Receptor Signaling Regulates DNA Repair in Prostate Cancers

William R. Polkinghorn, Joel S. Parker, Man X. Lee, +22

Cancer Discovery

Overcoming mutation-based resistance to antiandrogens with rational drug design

Minna Balbas, Michael J. Evans, David J. Hosfield, +7

eLife

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer

Neel Shah, Ping Wang, John Wongvipat, +11

eLife

Androgen ReceptorUrologyMedicineHormonal ReceptorCancer Genomics +10

Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer

Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu, +21

Nature Communications

Urine tumor DNA detection of minimal residual disease in muscle-invasive bladder cancer treated with curative-intent radical cystectomy: A cohort study

Pradeep S. Chauhan, Kevin Chen, Ramandeep K. Babbra, +17

PLoS Medicine