Christopher J. Applebee

Functional Engagement of the PD-1/PD-L1 Complex But Not PD-L1 Expression Is Highly Predictive of Patient Response to Immunotherapy in Non–Small-Cell Lung Cancer

Lissete Sánchez‐Magraner, Juan Gumuzio, James Miles et al. · Journal of Clinical Oncology · 2023 · 80 citations · Full text

Life Sciences, Immunology, Oncology +17

Regulation of 3-Phosphoinositide–Dependent Protein Kinase 1 Activity by Homodimerization in Live Cells

Thomas A. Masters, Véronique Calleja, Daven A. Armoogum et al. · Science Signaling · 2010 · 78 citations

Life Sciences, Cell Biology, Molecular Biology +8

High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment

Lissete Sánchez‐Magraner, James Miles, Claire L. Baker et al. · Cancer Research · 2020 · 47 citations · Full text

Life Sciences, Immunology, Oncology +17

The unprecedented membrane deformation of the human nuclear envelope, in a magnetic field, indicates formation of nuclear membrane invaginations

Régine Dazzoni, Axelle Grélard, Estelle Morvan et al. · Scientific Reports · 2020 · 39 citations · Full text

Life Sciences, Biophysics, Cell Biology +17

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

James Miles, Christopher J. Applebee, Pierre Leboucher et al. · BBA Clinical · 2017 · 10 citations · Full text

Medicine, Molecular Biology, Oncology +17