Alain Vigroux

Theoretical Studies of the Hydroxide-Catalyzed P−O Cleavage Reactions of Neutral Phosphate Triesters and Diesters in Aqueous Solution:  Examination of the Changes Induced by H/Me Substitution

Nathalie Iché-Tarrat, Jean‐Claude Barthelat, Daniel Rinaldi et al. · The Journal of Physical Chemistry B · 2005 · 53 citations

Natural Sciences, Chemistry, Catalysis +12

Diastereoselective Synthesis of a Conformationally Restricted Dinucleotide with Predefined α and β Torsional Angles for the Construction of α,β-Constrained Nucleic Acids (α,β-CNA)

Ingrid Le Clézio, Jean‐Marc Escudier, Alain Vigroux · Organic Letters · 2002 · 47 citations

Life Sciences, Biochemistry, Molecular Biology +17

Reactivity of Phosphate Monoester Monoanions in Aqueous Solution. 1. Quantum Mechanical Calculations Support the Existence of “Anionic Zwitterion” MeO⁺(H)PO₃²^- as a Key Intermediate in the Dissociative Hydrolysis of the Methyl Phosphate Anion¹

Marc Bianciotto, Jean‐Claude Barthelat, Alain Vigroux · Journal of the American Chemical Society · 2002 · 46 citations

Natural Sciences, Chemistry, Computational Chemistry +15

Watson–Crick Base‐Pairing Properties of Nucleic Acid Analogues with Stereocontrolled α and β Torsion Angles (α,β‐D‐CNAs)

Christelle Dupouy, Nathalie Iché‐Tarrat, Marie‐Pierre Durrieu et al. · Angewandte Chemie International Edition · 2006 · 39 citations

Life Sciences, Biochemistry, Molecular Biology +15

Cyclization-Activated Prodrugs: N-(Substituted 2-hydroxyphenyl and 2-hydroxypropyl)carbamates Based on Ring-Opened Derivatives of Active Benzoxazolones and Oxazolidinones as Mutual Prodrugs of Acetaminophen

Alain Vigroux, Michel Bergon, Chantal Zedde · Journal of Medicinal Chemistry · 1995 · 37 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8