Roy Schrijver

36th International Symposium on Intensive Care and Emergency Medicine

R. M. Bateman, Michael D. Sharpe, Justin E. Jagger et al. · Critical Care · 2016 · 521 citations · Full text

Life Sciences, Pharmacology, Physiology +17

Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis

Karin C.A.A. Wildhagen, Pablo Garcı́a de Frutos, Chris Reutelingsperger et al. · Blood · 2013 · 295 citations

Veterinary Medicine, Immunology, Pharmacology +12

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis

Tom Seijkens, Claudia M. van Tiel, Pascal Kusters et al. · Journal of the American College of Cardiology · 2018 · 194 citations · Full text

Life Sciences, Immunology, Pathobiology +16

Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients

Karin C.A.A. Wildhagen, Maryse A. Wiewel, Marcus J. Schultz et al. · Thrombosis Research · 2015 · 96 citations

Veterinary Medicine, Hematology, Molecular Biology +15

Discovery of Small Molecule CD40–TRAF6 Inhibitors

Barbara Zarzycka, Tom Seijkens, Sander B. Nabuurs et al. · Journal of Chemical Information and Modeling · 2015 · 95 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17