Evaluating In Vitro-In Vivo Extrapolation of Toxicokinetics

John F. Wambaugh, Michael F. Hughes, Caroline Ring, +12

Toxicological Sciences

Vitro-in Vivo ExtrapolationOral BioavailabilityPharmacokinetic ModelingAllergyPharmacological Study +11

Neurodevelopment and Thyroid Hormone Synthesis Inhibition in the Rat: Quantitative Understanding Within the Adverse Outcome Pathway Framework

Iman Hassan, Hisham El‐Masri, Patricia A. Kosian, +3

Toxicological Sciences

Developmental BiologyEndocrine MechanismBrain DevelopmentBrain MalformationIodine Deficiency Disorders +13

Developmental Thyroid Hormone Insufficiency Induces a Cortical Brain Malformation and Learning Impairments: A Cross-Fostering Study

Katherine L O’Shaughnessy, Patricia A. Kosian, Jermaine Ford, +3

Toxicological Sciences

NeuropsychologyDevelopmental Cognitive NeuroscienceBrain DevelopmentCross-fostering StudyLearning Impairments +25

A transient window of hypothyroidism alters neural progenitor cells and results in abnormal brain development

Katherine L O’Shaughnessy, Susan E. Thomas, Stephanie Spring, +3

Scientific Reports

Cumulative maternal and neonatal effects of combined exposure to a mixture of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) during pregnancy in the Sprague-Dawley rat

Justin M. Conley, Christy Lambright, Nicola Evans, +7

Environment International

Thyroid Disruptors: Extrathyroidal Sites of Chemical Action and Neurodevelopmental Outcome—An Examination Using Triclosan and Perfluorohexane Sulfonate

Mary E. Gilbert, Katherine L O’Shaughnessy, Susan E. Thomas, +8

Toxicological Sciences

Brain DevelopmentChemical ActionToxicological MechanismIodine Deficiency DisordersPotential Thyroid Disruptors +16

Gestational Exposure to Perchlorate in the Rat: Thyroid Hormones in Fetal Thyroid Gland, Serum, and Brain

Mary E. Gilbert, Iman Hassan, Carmen R. Wood, +4

Toxicological Sciences

Development of an<i>In Vitro</i>Human Thyroid Microtissue Model for Chemical Screening

Chad Deisenroth, Valerie Y. Soldatow, Jermaine Ford, +5

Toxicological Sciences

EngineeringImmunologyBiomedical EngineeringTh SynthesisTh Production +18

Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat

Iman Hassan, Hisham El‐Masri, Jermaine Ford, +4

Toxicological Sciences

Toxicological MechanismThyroperoxidase InhibitionMedicinal ChemistryParathyroid HormoneToxicology +15

Exploring the diversity of marine-derived fungal polyketide synthases

Kimberly M. Mayer, Jermaine Ford, Gordon R. Macpherson, +7

Canadian Journal of Microbiology

Bioorganic ChemistryEngineeringMolecular BiologyMarine Fungal IsolatesPhylogenetic Analysis +14