Concepedia

Matthias Frech

MF

Statistics

Publications

26

Citations

5.9K

H-Index

24

Active since

1988

Affiliations

Merck KGaA, Darmstadt (Germany)(Current)

Max Planck Institute for Medical Research

Max Planck Society

DKFZ-ZMBH Alliance

Instituto de Biologia Experimental e Tecnológica

Matthias Frech is an author at Merck KGaA, Darmstadt (Germany) specializing in life sciences, molecular biology, and biochemistry.

ORCID

Publications per year

1988–2022

26

Publications

26

Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

Jian-Ping Xiong, Thilo Stehle, Rongguang Zhang et al. · Science · 2002 · 1.6K citations

, , +17

Role of Translocation in the Activation and Function of Protein Kinase B

Mirjana Andjelković, Dario R. Alessi, Roger Meier et al. · Journal of Biological Chemistry · 1997 · 1.1K citations · Full text

, , +12

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

Matthias Frech, Mirjana Andjelković, Evan Ingley et al. · Journal of Biological Chemistry · 1997 · 444 citations · Full text

, , +14

Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules

Ute Krengel, Ilme Schlichting, Anna Scherer et al. · Cell · 1990 · 394 citations

, , +15

Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

Marta Amaral, Daria B. Kokh, Jörg Bomke et al. · Nature Communications · 2017 · 297 citations · Full text

, , +16

1–5 of 26