Aoife O’Shaughnessy-Kirwan

3D structures of individual mammalian genomes studied by single-cell Hi-C

Tim J. Stevens, David Lando, Srinjan Basu et al. · Nature · 2017 · 862 citations · Full text

Bioinformatics, Chromatin, Human Cell +13

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Daniel R. Barnes, Matti A. Rookus, Lesley McGuffog et al. · Genetics in Medicine · 2020 · 137 citations · Full text

Constraint of gene expression by chromatin remodelling protein CHD4 facilitates lineage specification

Aoife O’Shaughnessy-Kirwan, Jason Signolet, Ita Costello et al. · Development · 2015 · 75 citations · Full text

Genetics, Chromatin Remodelling Proteins, Lineage Commitment +21

The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

Inge M. M. Lakeman, Alexandra J. van den Broek, Julien A M Vos et al. · Genetics in Medicine · 2021 · 37 citations · Full text