A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

Yunkai Zhu, Fei Feng, Gaowei Hu, +17

Nature Communications

Global SpreadOff-target EffectGeneticsPathogenesisViral Pathogenesis +13

CRISPR/Cas9-mediated PD-1 disruption enhances human mesothelin-targeted CAR T cell effector functions

Wanghong Hu, Zhenguo Zi, Yanling Jin, +5

Cancer Immunology Immunotherapy

ImmunologyAutoimmunityGene EditingGenome EditingCellular Immune Response +5

EC5S Ubiquitin Complex Is Recruited by KSHV Latent Antigen LANA for Degradation of the VHL and p53 Tumor Suppressors

Qiliang Cai, Jason S. Knight, Suhbash C. Verma, +2

PLoS Pathogens

Cell RegulationMedicineImmunologyProtein DegradationLana Interaction +10

Kaposi's Sarcoma-Associated Herpesvirus Latent Protein LANA Interacts with HIF-1α To Upregulate RTA Expression during Hypoxia: Latency Control under Low Oxygen Conditions

Qiliang Cai, Ke Lan, Subhash C. Verma, +3

Journal of Virology

Lana BoundPrimary Effusion LymphomaImmunologyPathologyTumor Biology +16

Epstein–Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities

Fuming Yi, Abhik Saha, Masanao Murakami, +5

Virology

Tumor BiologyTargets P53ImmunologyApoptotic ActivitiesMedicine +5

Application of Improved Robot-assisted Laparoscopic Telesurgery with 5G Technology in Urology

Jianmin Li, Xuecheng Yang, Guangdi Chu, +23

European Urology

LaparoscopyUrologyRobotic TechnologyMinimally Invasive ProcedureRobotic Surgery +7

Epstein–Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of survivin

Jie Lu, Masanao Murakami, Subhash C. Verma, +5

Virology

Lymphoid NeoplasiaApoptosisImmunologyTumor ImmunityCell Death +9

The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8

Shuvomoy Banerjee, Jie Lu, Qiliang Cai, +4

PLoS Pathogens

Inhibits ApoptosisImmunologyViral PathogenesisPathologyCell Death +18

A Potential α-Helix Motif in the Amino Terminus of LANA Encoded by Kaposi's Sarcoma-Associated Herpesvirus Is Critical for Nuclear Accumulation of HIF-1α in Normoxia

Qiliang Cai, Masanao Murakami, Huaxin Si, +1

Journal of Virology

Hif-1alpha Nuclear AccumulationPathologyViral Structural ProteinCancer BiologyTumor Biology +18

Hypoxia Inactivates the VHL Tumor Suppressor through PIASy-Mediated SUMO Modification

Qiliang Cai, Suhbash C. Verma, Pankaj Kumar, +2

PLoS ONE