Zefei Xu

Asymmetric Synthesis of <i>N</i>‐Substituted α‐Amino Esters from α‐Ketoesters via Imine Reductase‐Catalyzed Reductive Amination

Peiyuan Yao, James R. Marshall, Zefei Xu et al. · Angewandte Chemie International Edition · 2021 · 67 citations · Full text

Biocatalytic Access to 1,4-Diazepanes via Imine Reductase-Catalyzed Intramolecular Asymmetric Reductive Amination

Zefei Xu, Peiyuan Yao, Xiang Sheng et al. · ACS Catalysis · 2020 · 58 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +16

Imine Reductase‐Catalyzed Enantioselective Reduction of Bulky α,β‐Unsaturated Imines en Route to a Pharmaceutically Important Morphinan Skeleton

Peiyuan Yao, Zefei Xu, Shanshan Yu et al. · Advanced Synthesis & Catalysis · 2018 · 38 citations

Pharmaceutical Science, Bioorganic Chemistry, Peptide Science +18

Asymmetric Synthesis of <i>N</i>‐Substituted 1,2‐Amino Alcohols from Simple Aldehydes and Amines by One‐Pot Sequential Enzymatic Hydroxymethylation and Asymmetric Reductive Amination

Yu Li, Na Hu, Zefei Xu et al. · Angewandte Chemie International Edition · 2022 · 36 citations

Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2-Arylethylamines via a Chemoenzymatic Approach

Linsong Yang, Jianjiong Li, Zefei Xu et al. · Organic Letters · 2022 · 24 citations

Bioorganic Chemistry, Fused-ring Alkaloids, Active Imine Reductases +20