Neuraminidase-1, a Subunit of the Cell Surface Elastin Receptor, Desialylates and Functionally Inactivates Adjacent Receptors Interacting with the Mitogenic Growth Factors PDGF-BB and IGF-2

Aleksander Hinek, Tetyana D. Bodnaruk, Severa Bunda, +2

American Journal Of Pathology

Developmental BiologySignal TransductionCell AdhesionReceptor (Biochemistry)Cell-matrix Interaction +8

PG490-88, a Derivative of Triptolide, Blocks Bleomycin-Induced Lung Fibrosis

Ganesh Krishna, Kela Liu, Hidenobu Shigemitsu, +3

American Journal Of Pathology

Antifibrotic TherapyInflammatory Lung DiseaseLung InflammationMedicinePulmonary Pharmacology +3

Retrovirally Mediated Overexpression of Versican V3 Reverses Impaired Elastogenesis and Heightened Proliferation Exhibited by Fibroblasts from Costello Syndrome and Hurler Disease Patients

Aleksander Hinek, Kathy R. Braun, Kela Liu, +2

American Journal Of Pathology

FibrosisMediated OverexpressionAutoimmune DiseaseDisease MechanismPathogenesis +7

Ellagic and Tannic Acids Protect Newly Synthesized Elastic Fibers from Premature Enzymatic Degradation in Dermal Fibroblast Cultures

Felipe Jimenez, Thomas F. Mitts, Kela Liu, +2

Journal of Investigative Dermatology

Tissue EngineeringEngineeringDermal Fibroblast CulturesWound HealingBiomedical Engineering +6

Induced Expression of Syndecan-1 in the Stroma of Head and Neck Squamous Cell Carcinoma

Perkins Mukunyadzi, Kela Liu, Ehab Y. Hanna, +2

Modern Pathology

Tumor BiologyMalignant DiseaseInduced ExpressionMedicinePathology +6

Heightened aberrant deposition of hard-wearing elastin in conduit arteries of prehypertensive SHR is associated with increased stiffness and inward remodeling

Silvia M. Arribas, Ana M. Briones, Catherine M. Bellingham, +5

American Journal of Physiology-Heart and Circulatory Physiology

HypertensionEngineeringBiomedical EngineeringBiomechanicsAberrant Deposition +15

Aldosterone Induces Elastin Production in Cardiac Fibroblasts through Activation of Insulin-Like Growth Factor-I Receptors in a Mineralocorticoid Receptor-Independent Manner

Severa Bunda, Peter Liu, Yanting Wang, +2

American Journal Of Pathology

Cardiac MuscleCardiomyopathyMedicinePhysiologyCardiac Fibroblasts +8

Proteolytic digest derived from bovine Ligamentum Nuchae stimulates deposition of new elastin-enriched matrix in cultures and transplants of human dermal fibroblasts

Aleksander Hinek, Yanting Wang, Kela Liu, +2

Journal of Dermatological Science

Regenerative MedicineTissue EngineeringHuman Dermal FibroblastsNew Elastin-enriched MatrixHuman Tissue +10

C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome

Michael Klüppel, Payman Samavarchi‐Tehrani, Kela Liu, +2

European Journal of Human Genetics

InflammationMusculoskeletal ResearchSignal TransductionPathologyOsteoarthritis +8

A novel, automated technology for multiplex biomarker imaging and application to breast cancer

G. Clarke, Judit Zubovits, Kashan Shaikh, +10

Histopathology