Hitoshi Yamashita

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

Sven Enerbäck, Anders Jacobsson, Elizabeth M. Simpson et al. · Nature · 1997 · 1.4K citations

Obesity, Metabolic Syndrome, Energy Homeostasis +9

Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.

Carmen Guerra, Robert A. Koza, Hitoshi Yamashita et al. · Journal of Clinical Investigation · 1998 · 631 citations · Full text

Metabolic Disorder, Immunology, Brown Fat +21

Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation

Tatsuo Furuyama, Kazuko Kitayama, Hitoshi Yamashita et al. · Biochemical Journal · 2003 · 323 citations · Full text

Muscle Function, Food Deprivation, Cellular Physiology +23

Randomized phase III study of bevacizumab plus FOLFIRI and bevacizumab plus mFOLFOX6 as first-line treatment for patients with metastatic colorectal cancer (WJOG4407G)

K. Yamazaki, Michitaka Nagase, H Tamagawa et al. · Annals of Oncology · 2016 · 274 citations · Full text

Gastrointestinal Oncology, Medicine, Pharmacology +9

UCP1 deficiency increases susceptibility to diet‐induced obesity with age

Yasuhide Kontani, Yifan Wang, Kazuhiro Kimura et al. · Aging Cell · 2005 · 208 citations · Full text