Characterization of phospholipase C activity at h5-HT 2C compared with h5-HT 2B receptors: influence of novel ligands upon membrane-bound levels of [ 3 H]phosphatidylinositols

Didier Cussac, Adrian Newman‐Tancredi, Yann Quentric, +5

Naunyn-Schmiedeberg s Archives of Pharmacology

Proteinlipid InteractionMolecular PhysiologySignal TransductionBiochemistryPhospholipase C Activity +11

Synthesis and pharmacological evaluation of thieno[2,3-b]pyridine derivatives as novel c-Src inhibitors

Isabelle Pévet, Cédric Brulé, André Tizot, +4

Bioorganic & Medicinal Chemistry

Medicinal ChemistryDerivative (Chemistry)MedicineNatural SciencesNovel C-src Inhibitors +9

Cyclization of Hydroxyenol Ethers into Spiroacetals. Evidence for the position of the transition state and its implication on the stereoelectronic effects in acetal formation

Normand Pothier, Solo Goldstein, Pierre Deslongchamps

Helvetica Chimica Acta

Transition StateStable IsomersDerivativesEngineeringBiochemistry +11

Synthesis, Structure, and Neuroprotective Properties of Novel Imidazolyl Nitrones

Alain Dhainaut, André Tizot, Eric Raimbaud, +3

Journal of Medicinal Chemistry

Novel Imidazolyl NitronesBiochemistryMedicine2-Phenylimidazolyl NitronePharmacological Agent +11

IAM retention and blood brain barrier penetration

André Ducarme, Michel Neuwels, Solo Goldstein, +1

European Journal of Medicinal Chemistry

Blood–brain BarrierNeurophysiologyMedicineIntracranial PressureBrain Injury +8

A short, economical, and stereoselective route to prostaglandins by vicinal alkylation of cyclopentadiene

Solo Goldstein, P. Vannes, C. HOUGE, +7

Journal of the American Chemical Society

Bioorganic ChemistryEngineeringAltmetric Attention ScoreOrganic ChemistryChemistry +15

Cytotoxic and antitumoral properties in a series of new, ring D modified, olivacine analogues

Claude Guillonneau, Annette Nault, Eric Raimbaud, +4

Bioorganic & Medicinal Chemistry

Olivacine AnaloguesMedicinal ChemistryPharmaceutical ScienceDerivative (Chemistry)Antitumoral Properties +8

Transannular Diels–Alder reactions on 14-membered macrocyclic trienes. Part II: formation of macrocycles and thermal conversion into tricyclic systems

Alexis Ndibwami, Serge Lamothe, Pierre Soucy, +2

Canadian Journal of Chemistry

Thermal ConversionChemical EngineeringIsomeric Acyclic TrienesDerivativesEngineering +9

<scp>S</scp> 50131 and <scp>S</scp> 51434, two novel small molecule glucokinase activators, lack chronic efficacy despite potent acute antihyperglycaemic activity in diabetic mice

Frédéric De Ceuninck, Catherine Kargar, Yves Charton, +9

British Journal of Pharmacology

Transannular Diels–Alder reactions on 14-membered macrocyclic trienes. Part I: stereoselective syntheses of the macrocyclic trienes precursors

Alexis Ndibwami, Serge Lamothe, Daniel Guay, +4

Canadian Journal of Chemistry

Chemical EngineeringEngineeringHeterocyclicTransannular Diels–alder ReactionsAlkene Metathesis +9