The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways

Qingqing Zhu, Lu Song, Guangdun Peng, +11

eLife

Epiblast Stem CellsSignaling PathwayNeural Fate CommitmentStem CellsCell Signaling +17

AAV-ie enables safe and efficient gene transfer to inner ear cells

Fangzhi Tan, Cenfeng Chu, Jieyu Qi, +14

Nature Communications

Dual Roles of Histone H3 Lysine 9 Acetylation in Human Embryonic Stem Cell Pluripotency and Neural Differentiation

Yunbo Qiao, Ran Wang, Xianfa Yang, +2

Journal of Biological Chemistry

Sperm epigenetic alterations contribute to inter- and transgenerational effects of paternal exposure to long-term psychological stress via evading offspring embryonic reprogramming

Xiaoguo Zheng, Zhenhua Li, Guishuan Wang, +6

Cell Discovery

The imbalance of Th17/Treg in patients with uterine cervical cancer

Yan Zhang, Daoxin Ma, Yong Zhang, +4

Clinica Chimica Acta

Tumoral PathologyCancer RiskCervical CancerMedicineGynecology +4

Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity

Jianan Li, Wenxia Yu, Shisheng Huang, +6

Nature Communications

Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis

Bo Ye, Dandan Fan, Weiwei Xiong, +11

Nature Communications

High-Risk Human Papillomavirus Reduces the Expression of MicroRNA-218 in Women with Cervical Intraepithelial Neoplasia

Y Li, J Liu, Cunzhong Yuan, +3

Journal of International Medical Research

Cervical Intraepithelial NeoplasiaImmunologyPathologyGynecologyTumor Biology +17

Phosphorylation of LIFR promotes prostate cancer progression by activating the AKT pathway

Jialiang Shao, Wencheng Zhu, Yufeng Ding, +8

Cancer Letters

Lifr PromotesUrologySignal TransductionSignaling PathwayCancer Progression +7

Distinct enhancer signatures in the mouse gastrula delineate progressive cell fate continuum during embryo development

Xianfa Yang, Boqiang Hu, Jiaoyang Liao, +13

Cell Research

Embryo DevelopmentCell LineageDevelopmental BiologyCell SpecializationGenetics +9